Androstenedione RIA
- Regulatory Status
- RUO
- Kit size
- 96
- Method
- RIA (CT)
- Incubation time
- 1 x 1h
- Standard range
- 0.1 - 11.0 ng / mL
- Specimen / Volumes
- 25 µL Serum , Plasma
- Substrate / isotope
- 125I < 111 kBq
Intended Use
Radioimmunoassay for the quantitative measurement of human 4-Androsten-3, 17-Dione (Androstenedione) in serum and plasma.
Biological Activity
4-Androsten-3, 17-dione (Androstenedione) is a C19 steroid. It is produced in the adrenal gland and gonads. Androstenedione is an immediate precursor to both testosterone and estrone, both of which may be subsequently converted to estradiol. Due to the presence of a 17-oxo (rather than hydroxyl) group, Androstenedione has relatively weak androgenic activity, estimated at ≤ 20 % of testosterone.
For research use only. Not for use in diagnostic procedures.
For concrete data please consult the Instruction for Use in the download box on the top right side.
- Dorfman RI, Shipley RA : Androgens. John Wiley and Sons, New York, pp. 116-128, 1956.
- Horton R, Tait J : Androstenedione production and interconversion rates measured in peripheral blood and studies on the possible site of its conversion to testosterone. J Endocrinol Invest 45:301-313,1966.
- Pang S, Riddick L : Hirsutism. IN Lifshitz T (ed) : Pediatric Endocrinology, A Clinical Guide, second edition. Marcel Dekker, Incl., New York, pp. 259-291, 1990.
- Cavallo A, Corn C, Bryan GT, Meyer WJ III : The use of plasma androstenedione in monitoring therapy of patients with congenital adrenal hyperplasia. J Pediatr 95:33-37, 1979. Bull NY Acad Med 53, 347, 1977
- Barett-Connor E, Garland C, McPhililips JB, Kaw K-T, Wingard DL : A prospective, population based study of androstenedione, estrogens and prostate cancer. Canc res 50:169-173, 1990.
- Rittmaster RS, Thompson DL : Effects of leuprolide and esametehasone o hair growth and hormone levels in hirsute women : the relative importance of the ovary and adrenal in the pathogenesis of hirsutism. J Clin Endocrinol Metab 70:112-116, 1993.
- Zwicker H, Rittmaster RS : Androsterone sulfate : Physiology and signifiance in hirsute women. J Clin Endocrinol Metab 76:112-116, 1993.
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Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
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