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Interleukin-22 / IL-22 (mouse) ELISA

Catalog no.BE45161
Regulatory Status
RUO
Kit size
12 x 8
Method
ELISA
Incubation time
1 x 2h, 1 x 1h, 1 x 10min.
Standard range
7.8 - 500 pg/ml
Specimen / Volumes
50µl serum, plasma, cell culture supernatant
Substrate / isotope
TMB 450 nm
instructions for useMSDS

IL-22 is a cytokine originally identified as a gene induced by IL-9 in murine T lymphocytes, and showing 22% amino acid identity with IL-10. IL-22 is produced by activated Th1 and NK cells acting primarily on epithelial cells and is involved in inflammatory responses. Neither resting nor activated immune cells express IL-22 receptor, and IL-22 does not have any effects on these cells in vitro and in vivo. In contrast, cells of the skin and the digestive and respiratory systems represent putative targets of this cytokine. Thus IL-22 does not serve the communication between immune cells but is a T cell mediator that directly promotes the innate, nonspecific immunity of tissues. IL-22 serves as a protective molecule to counteract the destructive nature of the immune response to limit tissue damage. Synonyms: ILD110, ILTIF, TIFa

For concrete data please consult the Instruction for Use in the download box on the top right side.

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Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.

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All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use. 

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