NF-light™ Serum ELISA
- Regulatory Status
- RUO
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 2h, 1 x 90min, 1 x 30min, 1 x 15min.
- Standard range
- 0.5 - 40 pg/mL
- Specimen / Volumes
- 100 µL serum
- Substrate / isotope
- TMB 450 nm
| MSDS |
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| MSDS |
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Serum NF-light™ ELISA is a Research Use Only assay for quantitative measurements of human Neurofilament light (NF-L) protein in serum samples. The kit is intended for professional use. The NF-light™ Serum ELISA can also be used for research on samples containing NF-L from rat, mouse, bovine or macaque sources as the antibodies in the assay recognizes NF-L from these species as well.
Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are important for the maintenance of the axonal caliber and morphological integrity, which affect the velocity and fidelity of neuronal transmissions. Three different neurofilament chains exist, named according to their size. These are Neurofilament light, medium and heavy respectively. The Neurofilament light constitutes the backbone to which the heavier chains co-assemble, forming the neurofilament fiber. Following injuries of nerve cells due to direct trauma or slow degenerative processes, the content of the cell is released into the surrounding compartment allowing quantitative determinations of the axonal proteins.
*distributed by TECAN - IBL International
Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
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