NF-light (Neurofilament-light) RUO ELISA
- Regulatory Status
- RUO
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 1h, 1 x 45min, 1 x 30min, 1 x 15min
- Standard range
- 100 - 10000 ng/L
- Specimen / Volumes
- 50 µL CSF
- Substrate / isotope
- TMB 450nm
The NF-Light™ (Neurofilament light) ELISA allows fast (3 hours) quantification of the neurofilament light chain. The assessment requires as little as 50 µL of CSF. Neurofilament light is found to be elevated in neurodegenerative disorders that are associated with the destruction of white matter (substantia alba).
The assay was developed by UmanDiagnostics, a company focusing on the development of immunochemical tools for research of neurological and traumatic injuries. The NF-Light™ (Neurofilament light) ELISA is exclusively distributed by IBL International.
Neurofilaments are the backbone of the neuronal cytoskeleton. Inside the axons, phosphorylation and dephosphorylation of the neurofilaments regulate, respectively, the expansion and contraction of the microtubules. The neurofilament light (NF-light) chain is the stoichiometrically most common form compared to other isoforms, such as medium and heavy chains. It is rapidly released after axonal destruction and remains highly stable (at least for 8 days, even at room temperature).
Distributed by TECAN, IBL International
For concrete data please consult the Instruction for Use in the download box on the top right side.
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Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
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