CIC-C1q ELISA
- Regulatory Status
- EU: CE
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 2 x 30 min., 1 x 15 min.
- Standard range
- 0 - 64µgEq/ml
- Specimen / Volumes
- 10µl serum, plasma
- Substrate / isotope
- TMB 450 nm
Enzyme immunoassay for the quantitative determination of CIC-C1q in human serum or plasma.Circulating immune complexes are present in many individuals with Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA), especially with any of the vasculitides complications. Levels of CICs have been reported to show correlation with disease activity in that higher levels are reported during active phases of the disease. Many tests have been developed for the detection of CICs, including PEG precipitation and radial immunodiffusion and cellular based assays such as the Raji cell assay. No single procedure appears to detect all types of CIC’s, however, those procedures which detect CIC’s containing fragments of complement (e.g. C1q and C3d) appear to detect clinically relevant events. C1q binds with greatest avidity to immune complexes ranging in size from 19 to 27 S. In serum sickness, which is the prototype immune complex disease, this size of complex has typically been found deposited in tissue leading to damage.
For concrete data please consult the Instruction for Use in the download box on the top right side.
Our Product Families
Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
And as experts in laboratory automation, we can support our customers with the protocols for open ELISA platforms, such as the Freedom EVOlyzer or Thunderbolt®.
All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use.
All of our assays have been designed and manufactured to meet the highest global regulatory requirements and quality standards. Tecan is certified under ISO 9001:2015, ISO 13485:2016 and is audited by a notified body according to Medical Device Single Audit Program (MDSAP).
This is who we are.
As part of the Tecan Group, we have a leading market position in diagnostics and research, with over 40 years of experience in the development, manufacture and supply of enzyme-, radiolabel- and luminescence-based immunoassays.
Our range of high-quality immunoassays is supported by a diverse portfolio of automated solutions, making us the perfect partner for you and your customers.
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