SCC ELISA
- Regulatory Status
- EU: CE
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 1 h, 1 x 30 min
- Standard range
- 1 - 50 µg/L
- Specimen / Volumes
- 25 µL serum
- Substrate / isotope
- TMB 405/620 nm
| instructions for use |
|---|
Squamous cell carcinoma antigen (SCC ag) is a group of glycoproteins with molecular weight ~45 kDa, belonging to the family of serine/cysteine -protease inhibitors (1). The protein was originally isolated by Kato and co-workers from human squamous cell carcinoma tissue and shown to consist of at least 10 subfractions differing in isoelectric point (2). More recent studies have shown that SCC antigen is composed of two distinct but highly homologous gene products, SCCA1 and SCCA2 with different inhibitor specificities (3). SCC antigen is a serological marker of squamous cell carcinomas of the uterine cervix, vulva, lung, head & neck, and oesophagus (4-6). In squamous cell carcinoma of the uterine cervix, pre-treatment serum SCC ag may be used as an early stage prognostic factor (7) and the use of pre-treatment SCC ag have been suggested in order to select high-risk patients for adjuvant therapy (4). Further, for patients with elevated levels of SCC ag before start of treatment, the profile of SCC ag correlates with the response to radio- and chemo-therapy and measurement of SCC ag may thus be used to monitor the effect of therapy and for early detection of recurrent disease.
For concrete data please consult the Instruction for Use in the download box on the top right side.
Our Product Families
Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
And as experts in laboratory automation, we can support our customers with the protocols for open ELISA platforms, such as the Freedom EVOlyzer or Thunderbolt®.
All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use.
All of our assays have been designed and manufactured to meet the highest global regulatory requirements and quality standards. Tecan is certified under ISO 9001:2015, ISO 13485:2016 and is audited by a notified body according to Medical Device Single Audit Program (MDSAP).
This is who we are.
As part of the Tecan Group, we have a leading market position in diagnostics and research, with over 40 years of experience in the development, manufacture and supply of enzyme-, radiolabel- and luminescence-based immunoassays.
Our range of high-quality immunoassays is supported by a diverse portfolio of automated solutions, making us the perfect partner for you and your customers.
Happy to help.
At Tecan, we are driven to improve people’s lives and health.