AIM/CD5L ELISA
- Regulatory Status
- RUO
- Kit size
- 12x8
- Method
- ELISA
- Incubation time
- 1x1h, 2x30min
- Standard range
- 0.78 - 50 ng/mL
- Specimen / Volumes
- 5 µL serum, EDTA plasma
- Substrate / isotope
- TMB 450 nm
Original article #27265.
AIM (Apoptosis Inhibitor of Macrophage) is produced by macrophages that are one type of immune cells, and it is a secreted form of protein that is secreted into blood.
It was named as “AIM” because of the function that suppresses apoptosis by acting on macrophage.
AIM level in serum increases along with obesity and it is taken up by adipose cells.
AIM decomposes triglyceride by suppression of Fatty Acid Synthase (FAS).
This is because it is suggested that AIM associates with various diseases such metabolic syndrome that is originated lifestyle diseases (arteriosclerosis and diabetes) and fatty liver.
In recent studies, it has been reported and suggested that it can be a therapeutic target for acute kidney injuries and liver cancer.
AIM binds to pentamer IgM in blood, but as the antibody used in this kit can detect IgM binding form, Total AIM can be quantitatively measured by this kit.
Distributed by IBL International
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