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Anti-human LRAT (Lecithin Retinol Acyltransferase) (031) Rabbit IgG

Catalog no.30116227
Quantity / Tests
50 µg
Species / Antigen
Synthetic peptide (GKDKGRNSFYETSSF)
Host
Rabbit
Subclass / Clone
IgG
Type
Polyclonal
Purification
Affinity Purification
Regulatory Status
RUO

"Original article #28153 LRAT is a retinol-esterifying enzyme and it is mainly found in G0 stage of stellate cells (Ito cells) in liver. At stellate cells, LRAT is thought to take a role engulfing and pooling excess vitamin A released from hepatocytes. As normal hepatocytes are characterized by lipid droplets pooling esterified vitamin A, LRAT is expected to be a marker of stellate cells in G0 stage. LRAT is also expressed in retinal pigment epithelium, small intestine epithelium and skin keratinocyte as well as liver. The physiological significance of LRAT protein at the endothelium is not clarified, yet. This antibody reacts with human stellate cells and endothelia."

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