Trichinella spiralis IgG ELISA
- Regulatory Status
- EU: CE
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 1h, 1 x 30min, 1 x 15min
- Standard range
- cut-off index
- Specimen / Volumes
- 10 µL serum, plasma
- Substrate / isotope
- TMB 450 nm
Trichinosis (also called trichinellosis) is caused by nematodes (roundworms) of the genus Trichinella. In addition to the classical agent Trichinella spiralis, which is found worldwide in many carnivorous and omnivorous animals, four other species (T. pseudospiralis, T. nativa, T. nelsoni, and T. britovi) are recognized. Trichinosis is acquired by ingesting meat containing cysts of Trichinella. After exposure to gastric acid and pepsin, the larvae are released from the cysts and invade the small bowel mucosa where they develop into adult worms (female 2.2 mm in length, males 1.2 mm). After 1 week, the females release larvae that migrate to the striated muscles where they encyst. Encystment is completed in 4 to 5 weeks and the encysted larvae may remain viable for several years. Ingestion of the encysted larvae perpetuates the cycle. Trichinosis infection occurs worldwide, but is most common in parts of Europe and the United States. Light infections may be asymptomatic. For mild to moderate infections, most symptoms subside within a few months whereas fatigue, weakness, and diarrhoea may last for months. In severe cases, death can occur. Infection may be identified by
Distributed by Tecan, IBL International GmbH.
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