LRG ELISA
- Regulatory Status
- RUO
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 1 h, 2 x 30 min
- Standard range
- 1.56 - 100 ng/mL
- Specimen / Volumes
- 100 µL CSF, serum, EDTA-plasma, urine
- Substrate / isotope
- TMB 450 nm
| instructions for use |
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Among the diseases which should be distinguished from iNPH (idiopathic normal pressure hydrocephalus) of elderly people showing symptoms such as gait disorder and dementia, there are some neurodegenerative diseases such as Alzheimer's disease, FTLD (frontotemporal lobar degeneration) and disorder associated with
Parkinson's disease. iNPH can be treated by a ventriculo-peritoneal shunt (VP shunt), so a marker in spinal fluid which can distinguish it from neurodegenerative diseases in an early stage has been required. Arai, Miyajima et al. had identified the high level of leucine-rich alpha-2-glycoprotein (LRG) in cerebrospinal fluid of iNPH patients, and they reported that measurement of LRG would be useful for differential identification of iNPH.
This ELISA kit can measure LRG in CSF, blood or urine. It has become possible to distinguish iNPH from neurodegenerative diseases such as Alzheimer's disease by measuring LRG in CSF. From now, early diagnosis and therapy of iNPH are expected to lead to the improvement of patient’s prognosis.
For concrete data please consult the Instruction for Use in the download box on the top right side.
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Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
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