α-Synuclein ELISA
- Regulatory Status
- RUO
- Kit size
- 12x8
- Method
- ELISA
- Incubation time
- 1x18h, 1x1h, 1x30min
- Standard range
- 0.16 - 100 ng/mL
- Specimen / Volumes
- 25 µL serum, plasma, CSF, cell culture supernatant
- Substrate / isotope
- TMB 450 nm
α-Synuclein is a 14.5kDa, soluble protein, which consists of 140 amino-acid residues and it is known as an intrinsically disordered protein. It is mainly expressed in cerebral neocortex, hippocampus, nigra, thalamus and metepencephalon. The majority of it exists in the presynaptic terminal and nucleus of neuron cells and it is considered to be involved in the signal regulatory system of the synaptic vesicle. α-Synuclein is the main structural component of Lewy bodies, which are inclusion bodies, that exist inside of neuron cells in neurodegenerative diseases called “Synucleinopathies” such as Parkinson's disease, dementia with Lewy body and multiple system atrophy. It is considered that excessive accumulation of α-Synuclein is the main cause of synucleinopathies due to induction of shedding of dopamine-producing cells. The concentration of α-Synuclein in human blood or human CSF can be quantitatively measured by this ELISA kit.
Our Product Families
Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
And as experts in laboratory automation, we can support our customers with the protocols for open ELISA platforms, such as the Freedom EVOlyzer or Thunderbolt®.
All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use.
All of our assays have been designed and manufactured to meet the highest global regulatory requirements and quality standards. Tecan is certified under ISO 9001:2015, ISO 13485:2016 and is audited by a notified body according to Medical Device Single Audit Program (MDSAP).
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As part of the Tecan Group, we have a leading market position in diagnostics and research, with over 40 years of experience in the development, manufacture and supply of enzyme-, radiolabel- and luminescence-based immunoassays.
Our range of high-quality immunoassays is supported by a diverse portfolio of automated solutions, making us the perfect partner for you and your customers.
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