Anti-TS (ATYMSMAB) Mouse IgG
- Quantity / Tests
- 100 µg
- Species / Antigen
- human
- Host
- mouse
- Subclass / Clone
- ATYMSMAB
- Type
- Monoclonal
- Purification
- Affinity Purification with protein A
- Regulatory Status
- RUO
Thymidylate synthase (TS; EC 2.1.1.45), Dihydropyrimidine dehydrogenase (DPD; EC 1.3.1.2), Thymidene phosphorylase (TP; EC 2.4.2.4) and Orate phosphorybosyl transferase (OPRT; EC 2.4.2.10) are known as key enzymes related to nucleic-acid metabolism within the body.
These enzymes are also known to be related to activation, metabolism and catabolism of 5-FU (5-fluorouracil) which is a metabolic antagonist being widely used for treatment of solid cancers including cancers of the digestive system and breast cancer. Some publications show a correlation between these enzymes and the effects of 5-FU-based anticancer drugs.
Additionally, TS and DPD have been reported to be prognosticating factors for individuals who suffer from these different cancers.
This antibody is useful for research of nucleic acid and expression of those proteins in cancer tissues.
Distributed by IBL International
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