IgA Saliva ELISA
- Regulatory Status
- EU: CE
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 1h, 1 x 15 min
- Standard range
- 6.9 - 400 µg/mL
- Specimen / Volumes
- 25 µL saliva
- Substrate / isotope
- TMB 450 nm
product information downloads
Intended use
Immunoenzymatic colorimetric method for quantitative determination of IgA in saliva. IgA Saliva ELISA kit is intended for laboratory use only.
Clinical significance
IgA represents about 15% to 20% of immunoglobulins in the blood, they are also found in the mucus secreted in the stomach, lungs and intestines. This prevents the microbes to bind to epithelial cells of the respiratory and digestive tract. This immunoglobulin helps to fight against pathogens that contact the body surface, are ingested, or are inhaled. It exists in two forms, IgA1 (90%) and IgA2 (10%) that differ in the structure. IgA1 is found in serum and made by bone marrow B cells, however IgA2 is made by B cells located in the mucosae and has been found to secrete into, colostrum, maternal milk, tears and saliva. The IgA found in secretions have a special form. They are dimeric molecules, linked by two additional chains. One of these is the J chain (from join), which is a polypeptide of molecular mass 1.5 kD, rich with cysteine and structurally completely different from other immunoglobulin chains. The dimeric form of IgA in the outer secretions also has a polypeptide of the same molecular mass (1.5 kD) called the secretory chain and is produced by epithelial cells. Decreased or absent IgA, termed selective IgA deficiency, can be a clinically significant immunodeficiency.
For concrete data please consult the Instruction for Use in the download box on the top right side.
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Our Product Families
Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
And as experts in laboratory automation, we can support our customers with the protocols for open ELISA platforms, such as the Freedom EVOlyzer or Thunderbolt®.
All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use.
All of our assays have been designed and manufactured to meet the highest global regulatory requirements and quality standards. Tecan is certified under ISO 9001:2015, ISO 13485:2016 and is audited by a notified body according to Medical Device Single Audit Program (MDSAP).
This is who we are.
As part of the Tecan Group, we have a leading market position in diagnostics and research, with over 40 years of experience in the development, manufacture and supply of enzyme-, radiolabel- and luminescence-based immunoassays.
Our range of high-quality immunoassays is supported by a diverse portfolio of automated solutions, making us the perfect partner for you and your customers.
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