Interferon-gamma (IFN-gamma) High Sensitivity ELISA

This High Sensitivity ELISA enables the analysis of Interferon-gamma in low concentrations from serum, plasma, or cell culture samples. The High Sensitivity ELISA Kits offer accurate quantification below conventional ELISA limits. This is made possible by their inherent design by amplifying the signal. IFN-gamma, also called Type II interferon, is a homodimeric glycoprotein containing approximately 21 to 24 kD subunits. The human IFN-gamma gene, situated on chromosome 12, contains three introns; the four exons code for a polypeptide of 166 amino acids, 20 of which constitute the signal peptide. In contrast to IFN-alpha and IFN-beta synthesis, which can occur in any cell, production of IFN-gamma is a function of T cells and NK cells. IFN-gamma has antiviral and antiparasitic activities and also inhibits the proliferation of a number of normal and transformed cells. IFN-gamma synergises with TNF-alpha and TNF-beta in inhibiting the proliferation of various cell types. Synonyms: Type II IFN