Total Estrogens ELISA
- Regulatory Status
- IVD
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 30 min, 1 x 120 min, 1 x 30 min
- Standard range
- 25 pg/mL – 2500 pg/mL
- Specimen / Volumes
- 150 μL Serum
- Substrate / isotope
- TMB 450 nm
| instructions for use |
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Intended Use
This Immunoassay is for the direct quantitative determination of Total Estrogens in human serum. For in vitro use only.
Summary and Explanation
Total estrogens comprise the total quantity of estrone, estradiol, and estriol. The estrogens are involved in the development of female sex organs and secondary sex characteristics. Before the ovum is fertilized, the main action of the estrogens is on the growth and function of the reproductive tract to prepare it for the fertilized ovum.
During the follicular phase of the menstrual cycle, the total estrogen level shows a slight increase. The production of total estrogens then increases markedly to peak at around day 13. The peak is of short duration and by day 16 of the cycle levels will be low. A second peak occurs at around day 21 of the cycle. If fertilization does not occur, the production of total estrogen decreases.
In post-menopausal women, the concentration of all estrogens decreases substantially and estrone becomes the predominant estrogen. In pregnant women, the concentration of all estrogen escalates and estriol becomes the predominant estrogen.
A total estrogen test is commonly indicated to:
- Aid in diagnosis of sex steroid metabolism-related conditions, for example, premature or delayed puberty, and aromatase and 17 alpha-hydroxylase deficiencies.
- Follow-up female hormone replacement therapy in post-menopausal women.
- Prognose antiestrogen therapy, for example, aromatase inhibitor therapy.
Distributed by Tecan, IBL International GmbH
For concrete data please consult the Instruction for Use in the download box on the top right side.
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Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
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All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use.
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