GPIHBP1 autoantibody ELISA
- Regulatory Status
- RUO
- Kit size
- 12 x 8
- Method
- ELISA
- Incubation time
- 1 x 1h, 2 x 30min.
- Standard range
- 0.008 - 0.500 U/mL
- Specimen / Volumes
- 10µL serum, plasma (EDTA, heparin, post-heparin)
- Substrate / isotope
- TMB 450 nm
GPIHBP1 (Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1) is an anchor protein that is modified by glycolipids and it has been known that it exists on a capillary endothelial cell membrane and is involved in the metabolism of triglyceride rich (TG-rich) lipoproteins (triglyceride). GPIHBP1 transports lipoprotein lipase (LPL) that is synthesized and secreted by adipocyte or skeletal muscle cells into capillary lumen and moors on the surface of endothelial cells. It has been revealed that GPIHBP1 has a significantly important role in TG-rich lipoprotein metabolism as it has been considered that a gene mutation of GPIHBP1 is a cause of type 1 hyperlipidemia (high chylomicronemia). This ELISA kit can measure GPIHBP1 in serum and plasma.
1. Adeyo, O., Goulbourne, C. N., Bensadoun, A., Beigneux, A. P., Fong, L. G., & Young, S. G. (2012). Glycosylphosphatidylinositol‐anchored high‐density lipoprotein‐binding protein 1 and the intravascular processing of triglyceride‐rich lipoproteins. Journal of internal medicine, 272(6), 528-540.
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Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
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