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Anti-human Girdin (Phosph-Y1764) Rabbit IgG

Catalog no.30112278
Quantity / Tests
50 µg
Species / Antigen
Synthetic peptide (RKTEDT(pY)FISSAG)
Host
Rabbit
Subclass / Clone
IgG
Type
Polyclonal
Purification
Affinity Purification
Regulatory Status
RUO

"Original article #28145 Girdin is a new protein playing an important role in the infiltration and metastasis of cancer cells. A new substance of protein kinase B, Girdin (Girders of actin filament) was discovered by a research group led by Takahashi et al., Nagoya University by screening using yeast two-hybrid method and was elucidated that Girdin has an important role for cell migration downstream of protein kinase B. It has been proven that Girdin is a new actin binding protein and it restructures actin fibers upon phosphorylation by protein kinase B and it is involved in formation of lamellipodia that are located at the leading edge of cells and play an important role for cell migration by functional analysis. Various antibodies inclusive phosphorylated Girdin antibodies are provided by IBL and it has been suggested that the change of condition of phosphorylated Girdin is involved in structure alteration in relation to cell migration in vivo or in vitro by current studies used these antibodies."

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