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GLP-1 (7-36/37) active forms HS ELISA

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Catalog no.30106821
Regulatory Status
RUO
Kit size
12 x 8
Method
ELISA
Incubation time
1 x 18h, 1 x 1h, 1 x 30 min.
Standard range
0.25 - 16 pmol/L
Specimen / Volumes
10µL rat, mouse and 50µL human plasma
Substrate / isotope
TMB 450 nm
instructions for use

Original article #27700 GLP-1 (Glucagon Like Peptide-1) is a transcriptional product of proglucagon gene as is glucagon and it is a gastrointestinal hormone secreted from L cells of lower section of the small intestine. GLP-1 (7-36) amide and GLP-1 (7-37) are active forms and these peptides are cleaved in blood by DPP4 (dipeptidyl peptidase-4) into GLP-1 (9-36) amide and GLP-1 (9-37) and these peptides lose its activities in a very short period. GLP-1 is known as an incretin as is GIP (Glucose-dependent Insulinotropic Polypeptide). It promotes secretion of insulin from β cells of the islets of Langerhans in the pancreas. GLP-1 also suppresses secretion of glucagon from α cells of the pancreas and the concentration of glucose in blood after meal. Drugs to treat type 2 diabetes have been developed by utilizing the functional mechanism of GLP-1 such as blood sugar control through pancreas, delayed gastric emptying and appetite suppression which contributes weight loss as extra-pancreatic effects. This ELISA kit can quantitatively and specifically measure GLP-1, active form (GLP-1(7-36) amide and GLP-1 (7-37)).

For concrete data please consult the Instruction for Use in the download box on the top right side.

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Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.

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All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use. 

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