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For the quantitiative measurement of Vasoactive Intestinal Polypeptide (VIP) in human EDTA plasma by an ELISA (Enzyme-Linked Immunosorbent Assay).
Vasoactive intestinal peptide (VIP) is a linear polypeptide containing 28 amino acid residues. The molecular weight is 3381. VIP is structurally related to secretin and to other members of the secretin family. The carboxyterminal amino acid of VIP (Asn) is amidated. Immunocytochemical studies have shown that VIP is present in neurons throughout the gastrointestinal tract, the centrol and peripheral nervous systems, the salivary glands and the pancreas. VIP stimulates water and bicarbonate secretion by the pancreas. VIP possesses the capacity to relax smooth muscle. Administration of VIP produces vasodilation and pulmonary bronchodilation and relaxes the lower eosophagaeal sphincter and smooth muscle of the fundus of the stomach. VIP is believed to play crucial roles in the regulation of intestinal motility and intestinal epithelial ion and water transport. Increased plasma immunoreactive VIP concentrations have been reported in patients with the WDHA syndrome (water, diarrhoea, hypokalemia and achlor hydria). Increased plasma levels of VIP have also been reported in patients with cirrhosis.
For Research Use Only. Not for use in diagnostic proceudres.
For concrete data please consult the Instruction for Use in the download box on the top right side.
Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
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