Human IL-17AF ELISA
- Regulatory Status
- RUO
- Incubation time
- 1 x 2h, 1 x 1h, 1 x 30min., 1 x 20min.
- Kit size
- 12 x 8
- Specimen / Volumes
- 100 μL supernatants, buffered solutions, serum, plasma
- Standard range
- 15.6 - 500 pg/mL
- Substrate / isotope
- TMB 450 nm
Intended use
The Human IL-17A/F ELISA kit is a solid phase sandwich ELISA for the in-vitro qualitative and quantitative determination of IL-17A/F in supernatants, buffered solutions or serum and plasma samples. This assay will recognise both natural and recombinant human IL-17A/F.
Summary
IL-17A and IL-17F are members of the IL-17 family that play crucial roles in allergic inflammation. They share the strongest homology and the two genes are located on the same chromosome region. Recent studies have shown that activated human CD4+T cells, termed Th17 cells, not only express IL-17A and IL-17F homodimers, but also an IL-17A/F heterodimer cytokine. IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent).
This kit has been configured for research use only. Not suitable for use in therapeutic procedures.
- Chang S.H. et.al, Cell Res. 2007 May;17(5):435-40.
- Kawaguchi M. et.al, J Allergy Clin Immunol. 2004 Dec;114(6):1265-73.
- Wright JF. et.al, J Biol Chem. 2007 May 4;282(18):13447-55.
- Wright JF. et.al, J Immunol. 2008 Aug 15;181(4):2799-805.
- Cheung P. et.al, J Immunol. 2008 Apr 15;180(8):5625-35.
Our Product Families
Our comprehensive immunoassay portfolio includes a number of specialty diagnostic immunoassays for endocrinology, immunology and autoimmunity, as well as for diagnosis of multiple infectious diseases. We are pioneers and market leaders in saliva diagnostics, with over 40 years of experience supplying a broad portfolio of luminescence- and ELISA-based tests, including our highly acclaimed HMGB1 and MuSK-Ab ELISAs.
And as experts in laboratory automation, we can support our customers with the protocols for open ELISA platforms, such as the Freedom EVOlyzer or Thunderbolt®.
All products are only available for sale to laboratory professionals and may not be available in all countries. Availability and regulatory status may vary across regions depending on local country-specific registration. Please always read and follow the instructions for use.
All of our assays have been designed and manufactured to meet the highest global regulatory requirements and quality standards. Tecan is certified under ISO 9001:2015, ISO 13485:2016 and is audited by a notified body according to Medical Device Single Audit Program (MDSAP).
This is who we are.
As part of the Tecan Group, we have a leading market position in diagnostics and research, with over 40 years of experience in the development, manufacture and supply of enzyme-, radiolabel- and luminescence-based immunoassays.
Our range of high-quality immunoassays is supported by a diverse portfolio of automated solutions, making us the perfect partner for you and your customers.
Happy to help.
At Tecan, we are driven to improve people’s lives and health.